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Undergraduate Record 2013-2014 [ARCHIVED RECORD]
Course Descriptions
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Biology |
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BIOL 3240 - Introduction to Immunology
Studies the genetics and cell biology of the vertebrate immune system, with a focus on adaptive immunity. Classic and current experimental systems are emphasized. Prerequisite: BIOL 2010, 2020.
Credits: 3
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BIOL 3250 - Introduction to Animal Behavior
An introduction to comparative studies of animal behavior from neuroethological and evolutionary prospectives. The first deals with proximate causes of behavior, with emphasis on motor, sensory and central aspects of the nervous system. The second deals with ultimate causes, with emphases on natural selection, natural history, and adaptive aspects of behavior. Prerequisite: BIOL 2010, 2020.
Credits: 3
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BIOL 3280 - Ornithology
This course is an introduction to avian biology. Major topics include evolutionary history, genetics, anatomy and physiology, behavior and communication, reproduction and development, and ecology and conservation. Through the study of birds, the most diverse lineage of terrestrial vertebrates, students learn broadly applicable concepts of organismal biology and gain insight to the scientific investigation of integrated biological systems. Prerequisite: BIOL 2010, 2020.
Credits: 3
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BIOL 3290 - Ecology and Conservation of Fishes
A laboratory course with a significant field component, an expanded version of a similar course taught at Mt. Lake Biological Station by the same instructor. Major topics of investigation center on the composition of freshwater fish assemblages and on the factors that influence distribution of fishes on multiple scales, from within stream reaches to among basins, including; physical habitat, water quality, and water flow; drainage histories and other zoo geographic processes; morphological, physiological, and life history characters of fishes; competition, predation and other biotic interactions; natural disturbance regimes; and anthropogenic impacts. The first portion of the semester provides an introduction to fish biology and systematics. Prerequisite: BIOL 2010, 2020, 2040.
Credits: 3
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BIOL 3360 - Biological Therapy of Cancer
This seminar course revolves around weekly two-hour student-led presentations of primary literature in the field of cancer therapy using novel approaches including immunotherapies. Objectives include providing the student with significant exposure to primary literature and the development of critical thinking skills. Prerequisites: Biology 3240
Credits: 2
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BIOL 3400 - Functional Morphology of Vertebrates
Comparative investigations of functional morphology across major vertebrate lineages. Lectures are organized into three units; 1) evolutionary history and patterns of development, 2) integumentary, skeletal and muscular systems, and 3) sensory systems, and neural and endocrine integrations. Topics of investigation focus on biomechanical and physiological performance of biological structures, from cells to organ systems, and on the origins and diversification of form-function complexes among vertebrates. Lab exercises include dissections, observation of prepared specimens and other material, and modeling/simulation of biomechanical systems. This course serves as a 3000-level lab requirement for either the B.A. or B.S. in biology. Prerequisite: BIOL 2010, 2020, 2040.
Credits: 4
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BIOL 3440 - Endocrinology
Endocrinology
Credits: 3
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BIOL 3450 - Biodiversity and Conservation
Introduction to the fundamental principles of conservation biology (e.g., global species numbers, value of biodiversity, causes of extinction, genetic diversity, island biogeography, priority setting) and current topics of debate (including zoo versus field conservation, effects of global change on species extinction). Conservation case studies will allow students to judge the relevance of biological theory to practical problems in conservation. Prerequisite: BIOL 2010, 2020 or EVSC 3200.
Credits: 3
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BIOL 3500 - Field Biology
Application of field techniques for biological studies. Cross-listed with EVSC 3660. Prerequisite: BIOL 2040 or instructor permission.
Credits: 1 to 3
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BIOL 3510 - Field Biology at Mountain Lake Biological Station
Field experiential courses in evolution, ecology, behavior and biology taught at the Biology Department’s Mountain Lake Biological Station (MLBS), a field research and teaching facility located in southwestern Virginia. Students may enroll for more than one section as each section is a specialized topic. Prerequisites: BIOL 2010, 2020, 2030, 2040 or AP credit or equivalent.
Credits: 1 to 4
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BIOL 3585 - Selected Topics in Biology
Tutorial or seminar course that allows intensive study of the literature in a particular area of biology under the guidance of a Biology faculty member.
Credits: 1 to 3
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BIOL 3650 - Molecular Biology of Human Disease
This course addresses molecular mechanisms of gene expression and regulation (e.g., transcription, mRNA splicing, RNA surveillance, and translation) and DNA replication in the context of infectious and genetic diseases.
Prerequisite: BIOL 2010 and any two of CHEM 1410, 1420, 1810 & 1820.
Credits: 3
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BIOL 3660 - Marine Biology and Coral Reef Ecology in San Salvador
The course will introduce students to the plants and animals found in the marine and terrestrial environments of the Caribbean and their adaptations in the context of community ecology. Fishes, invertebrates, reptiles and marine algae will be the major groups encountered and snorkeling will be used for observation and collection. Lectures, labs, discussions, and extensive field work included, plus an independent research project. Prerequisites: BIOL 2010, 2020, 2040, or EVSC 3200, or permission of the instructor.
Credits: 4
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BIOL 3665 - Tropical Ecology and Conservation in Belize
This course is an introduction to the organisms and ecosystems of Belize, including fresh water, marine and terrestrial examples. Special emphasis will be placed on the interactions of the ecosystem components and on the conservation of specific ecosystems and locales. Prerequisites: The completed sequence BIOL 2010, 2020, 2030, 2040, or their equivalents, or permission of instructor.
Credits: 3
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BIOL 3950 - Recent Advances in Biology
Consists of weekly lecture/discussion sessions on recent advances in biology as reported through articles in the current literature and in research seminars presented within the University. Required for DMP students. Prerequisite: Instructor permission. Note: All lecture courses at the 4000 level and above, have the prerequisite of at least one of the three core courses (3000-3020). All laboratory courses have a prerequisite of a 3000-level lab; unless a specific prerequisite lab is specified, any 3000-level lab will satisfy this prerequisite.
Credits: 3
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BIOL 4000 - Laboratory in Molecular Biology
Laboratory introduction to fundamental molecular techniques used in many biological research laboratories. Includes basic aseptic technique, isolation and manipulation of genetic material, electrophoresis, cloning, gene library construction/screening, Southern blot analysis, and PCR techniques. Lecture and open laboratory. Prerequisite: BIOL 3210.
Credits: 3
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BIOL 4020 - Ecology and Evolutionary Genetics
Examines the mechanisms of evolution within populations, molecular evolution, and the process of speciation. Topics include genetics of adaptation and speciation, natural selection, and the processes influencing the evolution of genes and genomes at the molecular level. Prerequisite: BIOL 3010.
Credits: 3
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BIOL 4030 - Evolutionary Biology Laboratory
Analyzes important concepts in evolution, and experimental techniques used in evolutionary ecology and population genetics field research, experimental populations, molecular markers, phylogenetic reconstruction including aspects of experimental design and statistical analysis of data. Includes a weekend field trip to Mountain Lake Biological Station. Prerequisite: BIOL 3010, MATH 1310.
Credits: 3
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BIOL 4040 - Laboratory in Cell Biology
Introduces students to experimental approaches, including mammalian cell culture, gel electrophoresis, western blotting and immunofluorescence microscopy, that are used to study both normal and pathological processes at the level of individual cells. The biological theme of the course will be Alzheimer’s disease (AD) and related neurodegenerative disorders. One laboratory lecture and one afternoon laboratory per week. Prerequisite: BIOL 3000
Credits: 3
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BIOL 4050 - Developmental Biology
Explores the processes of embryonic development in plants and animals, emphasizing the experimental basis of contemporary knowledge in embryo-genesis, morphogenesis and in cell and tissue differentiation. Lecture and occasional evening discussions. Prerequisite: BIOL 3010.
Credits: 3
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BIOL 4070 - Developmental Biology Laboratory
This course offers laboratory experience illustrating a number of principles and processes in the early development of both plants and animals. Laboratory work includes the use of basic microscopy and imaging techniques to study embryonic processes such as fertilization, oogenesis, gastrulation, and tissue interactions. Students will learn basic molecular techniques used to study gene expression and patterning in the embryo. Students will also develop skills in observation, experimental design, and data presentation. Prerequisite: BIOL 3000 and 3010.
Credits: 3
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BIOL 4080 - Neuronal Organization of Behavior
Lectures and discussions addressing behavior and sensory processing from the perspective of the neural elements involved. Topics include neuronal substrates (anatomical and physiological) of startle reflexes, locomotory behaviors, visual and auditory processing, echolocation mechanisms, calling song recognition, and the neuronal organization underlying some types of functional plasticity. Prerequisite: BIOL 3170 or equivalent.
Credits: 3
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BIOL 4100 - Management of Forest Ecosystems
Studies processes in forest ecosystems which effect management decisions. Emphasizes the interactions between the physiological processes of plants & system-level functions such as the cycling of nutrients & the flow of energy and water. Examples of current & projected uses of forest systems are discussed throughout, including harvesting for fiber & energy, and the preservation of forests as water purification and air pollution control systems. Prerequisites: EVSC 3200 or equivalent exposure to basic ecology is recommended.
Credits: 4
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BIOL 4110 - Genetics Laboratory
A research experience in developmental genetics that uses Drosophila melanogaster as a model system. Prerequisite: BIOL 3010.
Credits: 3
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BIOL 4120 - When Good Cells Go Bad
This course will cover topics related to major neurodegenerative diseases including Multiple Sclerosis (MS), Muscular Dystrophy (MD), Peripheral Nerve Sheath Tumor (Neurofibrosarcoma) and Malignant peripheral nerve sheath tumor (MPNST). Topics related to pathology and molecular mechanism of diseases, possible drug discovery targets, and therapeutic discovery approaches will be emphasized. Prerequisites: BIOL 3000, BIOL 3010.
Credits: 3
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BIOL 4130 - Population Ecology and Conservation Biology
The mathematical foundations of population dynamics and species interactions as applied to population and community ecology and problems in conservation biology. Prerequisite: BIOL 3020 or EVSC 3200, and a course in calculus.
Credits: 3
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BIOL 4140 - NextGen Sequencing and Its Applications
Students will learn the next generation sequencing technologies and explore their applications in the studies of evolution and ecology. This course is a lecture and journal club format where primary scientific literature will be discussed. Students will also learn basic bioinformatic skills.
Prerequisite: BIOL 3020
Credits: 1
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BIOL 4150 - Evolution of Sex
Despite the many benefits of asexual reproduction, the vast majority of eukaryotic organisms reproduce sexually. How sex evolved, and how it persists despite its many associated costs, are major unanswered questions in biology. We will explore the diversity of sexual reproduction and associated evolutionary phenomena with a focus on critically evaluating current research and theory in this field.
Prerequisite: BIOL 3020 or permission from Instructor
Credits: 3
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BIOL 4160 - Functional Genomics Lab
The course serves as a hands-on introduction to genomics, proteomics, and bioinformatics. Topics that will be covered during the lectures and computer labs of this course include genome sequence analysis, genome expression analysis, and genomic circuits analysis. Prerequisites: BIOL 3010.
Credits: 3
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BIOL 4170 - Cellular Neurobiology
Explores a cellular approach to the study of the nervous system. Topics include the structure and function of ionic channels in cell membranes; the electrochemical basis of the cell resting potential; the generation and conduction of nerve impulses; and synaptic transmissions. Three lecture and demonstration/discussion credits. Class meetings include lectures, discussion, student presentations, and computer simulations of neurophysiology with NeuroDynamix. Prerequisite: BIOL 3170 or equivalent; BIOL 3000.
Credits: 3
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BIOL 4180 - Behavioral Ecology
Behavioral ecology explores the evolutionary analysis and explanations for the diversity of animal behavior, including foraging decisions, altruism, cooperation, mate choice, group living, parental care and range of other sociobiological phenomena. Prereuaisite: BIOL 3020.
Credits: 3
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BIOL 4190 - Biological Clocks
Introduces biological timekeeping as used by organisms for controlling diverse processes, including sleep-wakefulness cycles, photoperiodic induction and regression, locomotor rhythmicity, eclosion rhythmicity, and the use of the biological clock in orientation and navigation. Prerequisite: BIOL 3000, 3010.
Credits: 3
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BIOL 4215 - Microbial Genomics
Explores how genomics has revolutionized every aspect of microbiology. Fundamental principles of microbiology, together with the basics of genomics will be introduced. Topics include microbial cell structure, metabolism, genetics, microbial diversity and ecology, epidemiology, genome sequencing technologies and comparative genomics. Prerequisites: BIOL 3000 and BIOL 3010
Credits: 3
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BIOL 4220 - Introduction to Systems Biology
An introduction to a new research paradigm that focuses on the systematic study of complex interactions at the molecular, network and genomic level. This course will review state-of-the-art high throughput techniques and modeling methods used to obtain, integrate and analyze complex data from biological systems. This course will be a combination of text based lectures and discussions of the current literature pertinent to Systems Biology. Prerequisites: BIOL 3010. Also recommended is BIOL 3000
Credits: 3
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BIOL 4240 - History and Philosophy of Biology
This course will give an overview of the major conceptual and experimental advances in Biology. It will explore the relationships of Biology to mathematics and physical sciences and explore philosophical issues relevant to science in general, Biology in particular. Prerequisite: 25 credits of Math or Science
Credits: 3
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BIOL 4250 - Human Genetics
Focuses on the fundamental knowledge about organization, expression, and inheritance of the human genome. Reviews classical Mendelian genetics and human genetic (pedigree) analysis. Emphasizes understanding human genetics in molecular terms. Includes gene mapping procedures, methodologies for identifying genes responsible for inherited diseases, the molecular basis of several mutant (diseased) states, the human genome project, and discussions about genetic screening and gene therapy. Prerequisite: BIOL 3010.
Credits: 3
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BIOL 4260 - Cellular Mechanisms
The course will explore topics in cell biology that underlie mechanisms of human health and disease. Specific topics will depend on interest, but may include cancer and metastasis, metabolic syndromes or pathogen-host interactions (among others). Course materials will be research and review articles from the relevant primary literature. Students are expected to engage in and lead thoughtful discussions of assigned readings ~75% of the class time. Prerequisites: BIOL 3000 and BIOL 3010
Credits: 3
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BIOL 4270 - Animal Behavior Laboratory
Provides direct experience in approaches used to study animal behavior. Each lab concentrates on a particular aspect of behavior. Student experiments relate to central nervous systems; sensory perception; sign stimuli, feeding behavior; social behavior; reproductive behavior; biological timing; and animal observation in the laboratory and field. Prerequisite: BIOL 3250 recommended.
Credits: 3
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BIOL 4280 - The Genetic Basis of Behavior
This course studies behavior paradigms in model animals and the modern genetic tools used study and dissect the circuits underlying them. Can an animal as simple as a fly or mouse learn simple tasks, show appetitive behaviors and cravings, and inform studies of human addiction? Readings from classic and current literature will show the historical context of this field and develop critical reading skills.
Prerequisites: BIOL 3000, BIOL 3010
Credits: 3
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BIOL 4290 - Hormones and Behavior
The aspects of hormones (primarialy sex and stress) on vertebrate behavior. Prerequisites: Any two of BIOL 3000, 3010, 3020 or equivalent.
Credits: 3
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BIOL 4310 - Sensory Neurobiology
This two-lectures-per-week course explores the basic principles of sensory neurobiology. The course consists of four modules. Each module represents one of the senses and consists of an introductory lecture, one or several lectures that will delve into the details of that sense, a current topic lecture on some recent finding, and finally, a guest lecture from a UVa researcher.
Prerequisites: BIOL 3170
Credits: 3
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BIOL 4320 - Signal Transduction: How cells talk to each other
This advanced undergraduate course explores how cells communicate with each other and respond to their environment. This area of biology is referred to as signal transduction and is the basis for most if not all normal and disease processes in humans. Therefore, significant time is spent on defining archetypal signaling modules that all cells use to receive and communicate information to and from their environment. Prerequisites: BIOL 3000 & BIOL 3010
Credits: 3
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BIOL 4330 - Wiring the Brain
This course will cover the current state of knowledge for how neurons form connections in the brain. The course will initially focus on how relatively simple model systems have provided the critical clues as to how specific synaptic connections form. This will be followed by a discussion of how this knowledge can be applied to the understanding and treatment of human neural disorders. About a quarter of the course will be standard lectures and the remainder student-led discussion of primary literature. Prerequisites: BIOL 3000 and BIOL 3010; BIOL 3170 or Psych 2200.
Credits: 3
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BIOL 4340 - Experimental Foundations of Neurobiology
The course content will focus on three areas of neurobiological research: conduction of the nervous impulse, sensory physiology, and synaptic physiology. Prerequisites: BIOL 3170 or an equivalent course
Credits: 3
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BIOL 4350 - Metabolic Systems
Examination of molecular mechanisms involved in metabolic regulation in mammals. Prerequiste: BIOL 3000, 3010.
Credits: 3
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BIOL 4360 - Cytokine Signaling and Neural Development
This is a journal club format seminar where we perform an in depth analysis of the papers listed below. One paper will be covered per week with a review article also assigned for background. There are no presenters; rather we will have discussion leaders. All participants should be prepared to present any of the panels in the week’s paper.
Credits: 1
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BIOL 4370 - Epigenetics
Explores the emerging science, Epigenetics. Topics include epigenetics in model organisms and molecular mechanisms such as the Polycomb and Trithorax Group proteins, histone modifications and variants, dosage compensation, DNA methylation, nuclear reprogramming and stem cell pluripotency. Prerequisites: Genetics and Molecular Biology, Cell Biology and Biochemistry strongly recomended.
Credits: 3
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BIOL 4380 - Evolution and Ecology of Development
From the seahorse’s body to the venus flytrap’s jaws to the human brain, nature abounds with amazing adaptations. This interdisciplinary course explores how and why such biodiversity evolves as well as what limits diversity. Lectures and case studies will focus on core concepts, recent advances, and integrative approaches, placing special emphasis on the interplay between gene regulatory networks, the environment, and population genetics.
Credits: 3
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BIOL 4410 - Molecular Biology and Genetics
A survey of contemporary issues in molecular biology and genetics. The course will be a combination of text based lectures and discussions of the current literature emphasizing the development of critical reading techniques. Prerequisites: BIOL 3000, 3010
Credits: 3
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BIOL 4480 - Macromolecular Structure
Exploration, in depth, of principles underlying protein and nucleic acid structures and the techniques used to determine those structures. Prerequisite: CHEM2410 and 2420 or BIOL3000 or permission of instructor
Credits: 3
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BIOL 4490 - Neural Systems and Behavior
This is an upper level lecture/discussion course for students interested in pursuing additional studies in neurobiology beyond the introductory level. Prerequisites: BIOL 3170 and BIOL 3250.
Credits: 3
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BIOL 4510 - Field Biology at Mountain Lake Biological Station
Field experiential courses in evolution, ecology, behavior and biology taught at the Biology Department’s Mountain Lake Biological Station (MLBS), a field research and teaching facility located in southwestern Virginia. Students may enroll for more than one section as each section is a specialized topic. Prerequisites: BIOL 3020 Evolution & Ecology or equivalent.
Credits: 1 to 4
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BIOL 4560 - Electric Crayfish: Elements of Neurophysiology
Course uses electrophysiological techniques with living crayfish material to examine principles of neurobiological function, including cellular resting potentials, propagated action potentials, neuromuscular physiology, aspects of neuromuscular organization, and sensory neuron physiology and organization. A lab lecture will precede each lab session. Grading will be based upon written laboratory reports and two midterm laboratory exams.
Prerequisite: BIOL 3170
Credits: 3
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BIOL 4585 - Selected Topics Course
Tutorial or seminar course that allows intensive study of the literature in a particular area of Biology under the guidance of a Biology faculty member
Credits: 1 to 3
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BIOL 4751 - Plant Diversity& Conservation: Bioinformatics and Systematics
The extraordinary diversity of the southern Appalachians will be used to explore the world of plants. We will visit unique mountain habitats to study the different species assemblages in these ecologically wide-ranging sites. Based upon our observations and analyses, we will critique contemporary views of the most effective conservation units (individual, population, species, family, habitat) and the methods used to achieve conservation goals.
Credits: 3
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BIOL 4752 - Field Methods in Stream Ecology
We will focus on integrating principles of stream and watershed ecology to gain insight into stream dwelling organisms and their environments. Students will be introduced to 1) the physical, chemical and biological organization of aquatic ecosystems, 2) current theories in stream and watershed ecology, and 3) lab and field methods for conducting stream research. Students will conduct independent and group research projects.
Credits: 3
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BIOL 4753 - Field Biology of Fungi
The southern Appalachians provide an ideal setting to explore the biology of fungi. This class provides an introduction with emphasis on fieldID and current experimental methods used to study fungal genetics, ecology, and evolution. Lab exercises will use filamentous fungi to demonstrate methods for identification, culture techniques, breeding systems, genetic analysis, and interaction biology. Field trips will survey the taxonomic diversity.
Credits: 3
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BIOL 4754 - Field Herpetology
The Southeast is a global hotspot of amphibian diversity. Activities will focus on the natural history, conservation, behavior, and ecology of local amphibians and reptiles. Students will learn methodology for identifying and monitoring amphibians and reptiles. Class will consist of lectures, field-based laboratories, and independent research projects, ranging from studying natural populations to conducting manipulative experiments.
Credits: 3
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BIOL 4755 - Field Biology of Fishes
MLBS sits on the Eastern Continental Divide providing an incredible diversity of freshwater habitats. Proficiency in ichthyology will be developed through field trips and coursework. Themes include: fish ID; patterns and drivers of diversity; interactions on individual, population, community and ecosystem levels; evolution; and influences of human activities. Students will design and conduct a research project and present at a class symposium.
Credits: 3
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BIOL 4756 - Field Ornithology
Students will be exposed to the biology, ecology, and evolutionary biology of birds through hands-on experience. Field exercises will teach how to identify birds by sight and sound, measure birds in hand, and monitor birds and their behaviors. These opportunities will be augmented with lectures on bird physiology, morphology, and diversity. Independent research projects will enable students to further develop their skills.
Credits: 3
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BIOL 4757 - GIS for Field Biologists
This course will cover the fundamentals of Geographic Information Systems as applied to biological questions with application in ecology, evolution, conservation, disease ecology, and human land-use. Students will learn spatial theory, analysis, and hands-on use of GIS software (including ArcGIS). Field laboratories will allow students to use Global Positioning Systems (GPS) and learn to incorporate this technology into spatial analyses.
Credits: 3
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BIOL 4810 - Distinguished Major Seminar in Biological Research I
Two-hour, weekly discussion of recent advances in biology; attend biology seminars, interact with seminar speakers, explore the philosophy and practice of science, and learn skills in oral and written research presentation. Prerequisite: Fourth-year DMP in Biology.
Credits: 2
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BIOL 4820 - Distinguished Major Seminar in Biological Research II
Two-hour, weekly discussion of recent advances in biology; attend biology seminars, interact with seminar speakers, explore the philosophy and practice of science, and learn skills in oral and written research presentation. Prerequisite: Fourth-year DMP in Biology.
Credits: 2
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BIOL 4850 - Seminar in Environmental and Conservation Biology
In-depth investigation of current research & practice in environmental and biological conservation. Format will include the discussion of fundamental & recent readings in conservation and guest speakers from the local scientific and conservation communities. Prerequisites for this class are BIOL 3450 and 3020. If interested students have taken EVSC 3020 instead of BIOL 3020, or other equivalent classes, contact the instructor for permission.
Credits: 2
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BIOL 4910 - Independent Research in the Life Sciences
Independent research for qualified undergraduates under the direction of a faculty member OUTSIDE of the Biology Department. Prerequisite: Instructor Permission
Credits: 2
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BIOL 4911 - Independent Research 1
Independent research for qualified undergraduates under the direction of a faculty member. Prerequisite: Instructor permission.
Credits: 2
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BIOL 4912 - Independent Research II
Independent research for qualified undergraduates under the direction of a faculty member. Prerequisite: Instructor permission and BIOL 4911.
Credits: 2
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BIOL 4913 - Independent Research III
Independent research for qualified undergraduates under the direction of a faculty member. Prerequisite: Instructor permission and BIOL 4912.
Credits: 2
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BIOL 4914 - Independent Research IV
Independent research for qualified undergraduates under the direction of a faculty member. Prerequisites: Instructor Permission and BIOL 4913.
Credits: 2
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BIOL 4915 - Independent Research V
Independent research for qualified undergraduates under the direction of a faculty member. Prerequisite: Instructor permission and BIOL 4914.
Credits: 2
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BIOL 4916 - Independent Research VI
Independent research for qualified undergraduates under the direction of a faculty member. Prerequisite: instructor permission and BIOL 4915.
Credits: 2
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BIOL 4917 - Independent Research VII
Independent research under the guidance of a departmental faculty member. Prerequisite: Instructor permission and BIOL 4916.
Credits: 2
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BIOL 4918 - Independent Research VIII
Independent research under the guidance of a departmental faculty member. Prerequisite: Instructor Permission and BIOL 4917
Credits: 2
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BIOL 4920 - Independent Research in Biology
Independent research for qualified undergraduates under the direction of a faculty member within the Biology Department. Prerequisite: Instructor Permission
Credits: 2
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BIOL 4993 - Independent Study In Biology
Tutorial or seminar course that allows intensive study of the literature in a particular area of biology under the guidance of a Biology faculty member.
Credits: 1 to 3
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BIOL 4994 - Independent Study in Biology
Independent study for qualified undergraduates under the direction of a faculty member. Prerequisite: Instructor permission and BIOL 4993.
Credits: 1 to 3
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BIOL 4995 - Independent Study
Independent study for qualified undergraduates under the direction of a faculty member.
Credits: 1-3
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Biomedical Engineering |
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BME 2000 - Biomedical Engineering Design and Discovery
Provides overview of the BME discipline and major sub-disciplines (biomechanics, genetic engineering, tissue engineering, bioelectricity, imaging, cellular engineering, computational systems biology), covers conceptual and detail design processes, and introduces quantitative tools utilized throughout the BIOM curriculum. A major focus of the class will be formulation and execution of a design project. Prerequisite: BME 2101, BME 3315, AND second-year status in Biomedical Engineering OR instructor permission.
Credits: 3
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BME 2101 - Physiology I for Engineers
We learn how excitable tissue, nerves and muscle, and the cardiovascular and respiratory systems function. You will develop an understanding of mechanisms, with an introduction to structure, an emphasis on quantitative analysis, and integration of hormonal and neural regulation and control. Prerequisites: intro courses in biology, chemistry, physics & calculus (BIOL 2010, CHEM 1610, PHYS 1425, APMA 1110 or similar) or instructor permission.
Credits: 3
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BME 2102 - Physiology II
Introduces the physiology of the kidney, salt and water balance, gastrointestinal system, endocrine system, and central nervous system, with reference to diseases and their pathophysiology. (Circulation and respiration are covered in the fall semester course, BME 2101). Prerequisite: BME 2101 or instructor permission.
Credits: 3
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BME 2104 - Cell and Molecular Biology for Engineers
Introduces the fundamentals of cell structure and function, emphasizing the techniques and technologies available for the study of cell biology. A problem-based approach is used to motivate each topic. Divided into three general sections: cell structure and function includes cell chemistry, organelles, enzymes, membranes, membrane transport, intracellular compartments and adhesion structures; energy flow in cells concentrates on the pathways of glycolysis and aerobic respiration; information flow in cells focuses on modern molecular biology and genetic engineering, and includes DNA replication, the cell cycle, gene expression, gene regulation, and protein synthesis. Also presents specific cell functions, including movement, the cytoskeleton and signal transduction. Prerequisite: CHEM 1610 or instructor permission.
Credits: 3
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BME 2220 - Biomechanics
Introduction to principles of continuum mechanics of biological tissues and systems. Topics include development of selected fundamental methods and results from statics and strength of materials, continuum mechanics, free-body diagrams, and constitutive equations of biological materials. Properties of blood vessels, heart, bone, cartilage, ligaments, tendons, blood, and other tissues. Mechanical basis and effects of pathology and trauma.
Prerequisites: APMA 2130, BME 2101, or permission of instructor.
Credits: 3
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BME 2240 - Biotransport
Biotransport in biological living systems is a fundamental phenomenon important in all aspects of the life cycle. Course will introduce principles and application of fluid and mass transport processes in cell, tissue and organ systems. Topics include, introduction to physiological fluid mechanics in the circulation and tissue, fundamentals of mass transport in biological systems, effects of mass transport and biochemical interactions at the cell and tissue scales, and fluid and mass transport in organs. Prerequisites: APMA 2120, 2130, BME 2101, BME 2104 or instructor permission.
Credits: 3
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BME 3080 - Biomedical Engineering Integrated Design and Experimental Analysis (IDEAS) Laboratory I
First half of a year-long course to integrate concepts and skills from prior courses in order to formulate and solve problems in biomedical systems, including experimental design, performance, and analysis. Lab modules include testing in tissues/cells and manipulation of molecular constituents of living systems to determine their structural and functional characteristics for design of therapeutic or measurement systems. Methods include biochemical, physiological, cell biology, mechanical, electrical and computer, systems, chemical, imaging, and other approaches. Prerequisite: APMA 2120, APMA 2130, APMA 3110, BME 2101, BME 2104, and BME 2220, or instructor permission; corequisite: BME 3310 or instructor permission.
Credits: 4
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BME 3090 - Biomedical Engineering Integrated Design and Experimental Analysis (IDEAS) Laboratory II
Second half of a year-long course to integrate the concepts and skills from prior courses in order to formulate and solve problems in biomedical systems, including experimental design, performance, and analysis. Lab modules include testing in tissues/cells and manipulation of molecular constituents of living systems to determine their structural and functional characteristics and to design measurement or therapeutic systems. Methods include biochemical, physiological, cell biology, mechanical, electrical and computer, systems, chemical, imaging, and other approaches. Prerequisite: BIOM 3080 or instructor permission.
Credits: 4
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BME 3310 - Biomedical Systems Analysis and Design
Presents the analytical tools used to model signals and linear systems. Specific biomedical engineering examples include multicompartment modeling of drug delivery, modeling of dynamic biomechanical systems, and electrical circuit models of excitable cells. Major topics include terminology for signals and systems, convolution, continuous time Fourier transforms, Laplace transforms, electrical circuits with applications to bioinstrumentation and biosystems modeling, and applications of linear system theory. Students cannot receive credit for both this course and ECE 3750. Prerequisite: APMA 2130, CS 1110 or instructor permission.
Credits: 3
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BME 3315 - Computational Biomedical Engineering
Introduces computational techniques for solving biomedical engineering problems & constructing models of biologic processes. Numerical techniques include regression, interpolation, differentiation, integration, root finding, systems of equations, optimization and approaches to ordinary differential equations. Applications include bioreactors, biotransport, pharmacokinetics & biomechanics. Prereq: APMA 2120 & CS 1110; recommended co-req APMA 2130.
Credits: 3
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BME 3636 - Neural Network Models of Cognition and Brain Computation
An introductory course to neural networks research, specifically biologically-based networks that reproduce cognitive phenomena. The goal of this course is to teach the basic thinking and methodologies used in constructing and understanding neural-like networks. Cross-listed as NESC 5330. CS 1110; and BIOM 2101; or permission of the instructor.
Credits: 3
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BME 4063 - Biomedical Engineering Capstone Design I
A year-long design project in biomedical engineering required for BME majors. Students select, formulate, and solve a design problem either for a device or system ‘design & build’ project or a ‘design of experiment’ research project. Projects use conceptual design, skills obtained in the integrated lab, and substantial literature and patent reviews. Projects may be sponsored by BME faculty, medical doctors, and/or companies. Students may work on their own with outside team members when appropriate or with other SEAS students in integrative teams. Prerequisite: APMA 2120, 2130, 3110, BME 2101, 2104, 3080, 3310, fourth-year standing in BME major, or instructor permission.
Credits: 3
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BME 4064 - Biomedical Engineering Capstone Design II
A year-long design project in biomedical engineering required for BME majors. Students select, formulate, and solve a design problem either for a device or system ‘design & build’ project or a ‘design of experiment’ research project. Projects use conceptual design, skills obtained in the integrated lab, and substantial literature and patent reviews. Projects may be sponsored by BME faculty, medical doctors, and/or companies. Students may work on their own with outside team members when appropriate or with other SEAS students in integrative teams. Prerequisite: APMA 2120, 2130, 3110, BME 2101, 2104, 3080, 3310, fourth-year standing in BME major, or instructor permission.
Credits: 3
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BME 4280 - Motion Biomechanics
Focuses on the study of forces (and their effects) that act on the musculoskeletal structures of the human body. Based on the foundations of functional anatomy and engineering mechanics (rigid body and deformable approaches); students are exposed to clinical problems in orthopedics and rehabilitation. Prerequisite: BME 2101, 2220, or instructor permission.
Credits: 3
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BME 4414 - Biomaterials
This course will provide an introduction to biomaterials science and biological interactions with materials, including an overview of biomaterials testing and characterization. The emphasis of this course, however, will be on emerging novel strategies and design considerations of biomaterials. Areas of concentration will include the use of polymers and ceramics in biomaterials today, drug delivery applications, tissue engineering from both an orthopaedic and vascular perspective, and nanotechnology related to biomaterials. Specific attention will also be paid to the in vitro and in vivo testing of biomaterials, and a review of current research in the field. Prerequisite: BME 2101, BME 2104 or equivalent, 3rd or 4th year standing, or instructor permission.
Credits: 3
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BME 4417 - Tissue Engineering
Introduces the fundamental principles of tissue engineering. Topics include: tissue organization and dynamics, cell and tissue characterization, cell-matrix interactions, transport processes in engineered tissues, biomaterials and biological interfaces, stem cells and interacting cell fate processes, and tissue engineering methods. Examples of tissue engineering approaches for regeneration of cartilage, bone, ligament, tendons, skin and liver are presented. Prerequisite: APMA 2130, BME 2101, and BME 2104 or equivalent, or instructor permission.
Credits: 3
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BME 4550 - Special Topics in Biomedical Engineering
Applies engineering science, design methods, and system analysis to developing areas and current problems in biomedical engineering. Topics vary by semester. Recent topics include Medical Imaging Systems Theory, BME Advanced Design, BME Electronics Lab, and Systems Biology Modeling and Experimentation. Prerequisite: third- or fourth-year standing and instructor permission.
Credits: 3
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BME 4641 - Bioelectricity
Studies the biophysical mechanisms governing production and transmission of bioelectric signals, measurement of these signals and their analysis in basic and clinical electrophysiology. Introduces the principles of design and operation of therapeutic medical devices used in the cardiovascular and nervous systems. Includes membrane potential, action potentials, channels and synaptic transmission, electrodes, electroencephalography, electromyography, electrocardiography, pacemakers, defibrillators, and neural assist devices. Prerequisite: BME 3310 or ECE 2630, BME 2101, or instructor permission.
Credits: 3
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BME 4783 - Medical Imaging Modalities
An overview of modern medical imaging modalities with regard to the physical basis of image acquisition and methods of image reconstruction. Topics cover the basic engineering and physical principles underlying the major medical imaging modalities: x-ray (plain film, mammography, and computed tomography (CT)), nuclear medicine (positron-emission tomography (PET) and single-photo-emission computed tomography (SPECT)), ultrasound, and magnetic resonance imaging (MRI). Prerequisite: BME 3310 or ECE 3750, or instructor permission.
Credits: 3
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BME 4784 - Medical Image Analysis
Introduces the fundamental principles of medical image analysis and visualization. Focuses on the processing and analysis of ultrasound, MR, and X-ray images for the purpose of quantitation and visualization to increase the usefulness of modern medical image data. Includes image perception and enhancement, 2-D Fourier transform, spatial filters, segmentation, and pattern recognition. A weekly lab develops skill in computer image analysis with the KHOROS system. Prerequisite: BME 3310, ECE 3750, or instructor permission.
Credits: 4
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BME 4806 - Biomedical Applications of Genetic Engineering
Provides biomedical engineers with a grounding in molecular biology and a working knowledge of recombinant DNA technology, thus establishing a basis for the evaluation and application of genetic engineering in whole animal systems. Beginning with the basic principles of cell structure and function, this course examines the use of molecular methods to study gene expression and its critical role in health and disease. Topics include DNA replication, transcription, translation, methods for studying genes and gene expression at the mRNA and protein levels, methods for mutating genes and introducing genes into cells, methods for creating genetically-engineered mice and methods for accomplishing gene therapy by direct in vivo gene transfer. Prerequisite: BME 2101, 2102, and 2104, or CHE 2246, and third- or fourth-year standing, or instructor permission.
Credits: 3
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BME 4890 - Nanomedicine
Students will design treatment strategies for cancer and cardiovascular disease based on molecular bioengineering principles. Special topics will include design of nanoparticle drug and gene delivery platforms, materials biocompatibility, cancer immunotherapy, and molecular imaging. Prerequisite: BME 2104 or CHE 2246, BME 2220, fourth-year standing, or instructor permission; Recommended: BME 2240
Credits: 3
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BME 4993 - Independent Study
In-depth study of a biomedical engineering area by an individual student in close collaboration with a departmental faculty member. Requires advanced analysis of a specialized topic in biomedical engineering that is not covered by current offerings. Requires faculty contact time and assignments comparable to regular course offerings. Prerequisite: instructor permission.
Credits: 1 to 3
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